XYREM Success Program^® for Patients

To support patients in obtaining and using XYREM^®, Jazz Pharmaceuticals along with the FDA developed the XYREM Success Program^® for Patients. This program includes educational materials about XYREM, and toll-free access to the XYREM central pharmacy (SDS Pharmacy) where specially-trained staff are available to answer questions 24 hours a day/7 days a week. The XYREM Success Program makes sure that XYREM is distributed and used in a safe way.

1-866-XYREM88^® (1-866-997-3688)

Once your doctor has faxed your XYREM prescription to SDS Pharmacy with the XYREM Success Program:

• An SDS Pharmacy team member will check to make sure the prescription is valid.
• An Admissions Specialist will then call you within 48 hours to review your insurance coverage. (See the question on next page, “Is XYREM covered by insurance?”)
• An SDS Pharmacy team member will schedule your shipment with you. The team member will confirm that you have read and understood the XYREM Success Program educational materials. If your doctor did not give these materials to you, SDS Pharmacy will mail them to you before or with your first shipment of XYREM.

SDS Pharmacy will always confirm where and when you would like your XYREM delivered. They will also confirm who will sign for your shipment. This person must be at least 18 years old. It can be you or someone you choose.

XYREM will be shipped via overnight delivery service. You or your designee must sign for the shipment. Your designee’s name will be kept on file. SDS Pharmacy will match the delivery signature to the one it has on file. They will also call you to make sure you got your shipment.

If SDS Pharmacy can’t reach you, an SDS Pharmacy team member will leave a phone message and ask you to call back. The toll-free number (1-866-997-3688) of the SDS Pharmacy will show up on caller ID. The words “Express Scripts” may also appear.

XYREM is a medication that has been approved for the treatment of excessive daytime sleepiness and cataplexy in patients with narcolepsy. Important information about XYREM includes the following:

• Twice nightly dosing: the first dose is taken at bedtime and the second dose 2½ – 4 hours later.
• Both doses should be taken while sitting up in bed.
• XYREM should not be taken with alcohol or other medications that cause drowsiness.
• Your XYREM prescription is filled and sent by a central, mail order pharmacy.
• The active ingredient of XYREM is a form of GHB and has been a target for persons who abuse drugs. Therefore your XYREM must be used only by you, only as directed by your physician, and stored in a safe, secure place, away from children and pets.

For more safety information, see the complete safety information and storage and safety tips at home.