Xyrem is a prescription medicine used to treat the following symptoms in people who fall asleep frequently during the day, often at unexpected times (narcolepsy):
Xyrem may only be given to patients enrolled in the Xyrem Success Program.
Xyrem is available only by prescription and filled through the central pharmacy in the Xyrem Success Program. Before you receive Xyrem, your doctor or pharmacist will make sure that you understand how to use Xyrem safely and effectively. If you have any questions about Xyrem, ask your doctor or call the Xyrem Success Program® at 1-866-997-3688.
Xyrem is approved in adults. It is not known if it is safe and effective in children. Xyrem is a controlled substance (CIII) because it contains sodium oxybate that can be a target for people who abuse prescription medicines or street drugs. Keep your Xyrem in a safe place to protect it from theft. Never give your Xyrem to anyone else because it may cause death or harm them. Selling or giving away this medicine is against the law.
Do not take Xyrem if you take other sleep medicines or sedatives (medicines that cause sleepiness), drink alcohol, or have a rare problem called succinic semialdehyde dehydrogenase deficiency.
Before you take Xyrem, tell your doctor if you:
If you have been prescribed XYREM, see Getting Started with XYREM for information and tips on how to safely fill, take, and store your XYREM prescription.
Talk with a XYREM Patient Connection Mentor
The XYREM Patient Connection program provides an opportunity for you to talk one-on-one with a mentor who has been diagnosed with excessive daytime sleepiness and/or cataplexy with narcolepsy, and has been treated with XYREM.