HOw DOES XYREM wORK IN MY BODY?

HOw DOES XYREM
wORK IN MY BODY?

XYREM has been shown to have reduced bioavailability when taken with food.1,2

In a XYREM clinical study...

  • Both mean peak plasma concentrations and mean amount of XYREM exposure decreased when taken with food.1,2
  • Patients should be reminded...
    • To wait at least 2 hours after eating before they take their first dose of XYREM, because food significantly reduces the bioavailability of XYREM.1

Mean Oxybate Plasma Concentration Following a Single
4.5-g Oral Dose in Healthy Volunteers2*

Mean Oxybate Plasma Concentration Following a Single 4.5-g Oral Dose in Healthy Volunteers

*Mean oxybate concentration (± SEM) vs time after a single 4.5-g oral dose of XYREM in 34 healthy volunteers.2
Single doses greater than 4.5 g have not been studied.1

Figure adapted with permission from Borgen et al, 2003.

Dosage

Find out about how to
properly dose XYREM.

Starting &
Titrating XYREM
Counseling

Find out about counseling
patients on how to take
XYREM.

Setting a routine