Role of the Certified PharmacY

XYREM will be dispensed only by the specially certified central pharmacy1

Prescribers should refer to the XYREM® REMS Program Prescriber Brochure for details on the role of the Certified Pharmacy. Available at XYREMREMS.com.

Following the receipt of a patient’s prescription, the Certified Pharmacy will1:

Provide confirmation of each new XYREM REMS Program Prescription Form received.

Contact the patient’s insurance provider to verify XYREM prescription benefits.

Prior to the first shipment, contact the patient to:

  • Confirm whether he or she has received a copy of the XYREM REMS Program Patient Quick Start Guide; the Certified Pharmacy will send a copy of the XYREM REMS Program Patient Quick Start Guide to any patient not previously receiving one from his or her prescriber.
  • Counsel the patient on expectations from XYREM therapy and how to prepare and take XYREM doses safely and effectively.
  • Review important XYREM safety information and precautions for XYREM use.
  • Review XYREM safe handling and storage procedures.
  • Review the adverse events associated with XYREM use.
  • Review the patient’s use of concomitant medications. You will be notified of any potential for drug interactions based on patient counseling.
  • Ask if the patient has any questions about XYREM and answer the questions and/or refer the patient back to the prescriber, as appropriate.

Dispense and ship XYREM by overnight service to the patient or his or her authorized adult designee.

Remind patients about monthly refills.

Contact the prescriber if a prescription refill or renewal is required.

Provide 24/7 toll-free telephone access to pharmacist support for prescribers, office staff, and patients by answering questions about safety, dosing, and patient care.

The Certified Pharmacy provides support for completion of required REMS Enrollment and Prescription Forms.

Need Help? Have Questions?

Call the XYREM REMS Program hotline anytime.

The Certified Pharmacy provides 24/7 toll-free access to a pharmacist to help answer any questions or concerns the prescriber, office staff, or patients may have regarding safety, dosing, and patient care.

Frequently Asked Questions

Following receipt of a patient’s prescription, the Certified Pharmacy will1:

  • Provide confirmation of each new XYREM REMS Program Prescription Form received
  • Contact the patient’s insurance provider to verify XYREM prescription benefits
  • Prior to the first shipment, contact the patient to:
    • Confirm whether he or she has received a copy of the XYREM REMS Program Patient Quick Start Guide; the Certified Pharmacy will send a copy of the XYREM REMS Program Patient Quick Start Guide to any patient not previously receiving one from his or her prescriber
    • Counsel the patient on expectations from XYREM therapy and how to prepare and take XYREM doses safely and effectively
    • Review important XYREM safety information and precautions for XYREM use
    • Review XYREM safe handling and storage procedures
    • Review the adverse events associated with XYREM use
    • Review the patient’s use of concomitant medications
      • You will be notified of any potential for drug interactions based on patient counseling.
    • Ask if the patient has any questions about XYREM and answer the questions and/or refer the patient back to the prescriber, as appropriate
  • Provide 24/7 toll-free telephone access to pharmacist support for prescribers, office staff, and patients by answering questions about safety, dosing, and patient care
  • Dispense and ship XYREM by overnight service to the patient or his or her authorized adult designee
  • Remind patients about monthly refills
  • Contact the prescriber if a prescription refill or renewal is required

Yes. The Certified Pharmacy provides 24/7 access to pharmacists.1

In addition, the Certified Pharmacy offers support for answering questions concerning the completion of required XYREM REMS Program Prescriber and Patient Enrollment Forms and the XYREM REMS Program Prescription Form.1

During counseling, the Certified Pharmacy will ask patients about their concomitant medications and conduct a drug utilization review for each patient. The Certified Pharmacy will also utilize First Databank’s electronic drug utilization review to see if any other prescription claims were processed for other medications that the patient may currently be taking. A pharmacist will continue to contact the prescriber if a possible serious drug interaction is uncovered, after reaching out to the patient to see if he or she is still taking that medication.1