Learn about all the support and savings opportunities that may be available to you while you are taking XYREM.

Please click here to see Important Safety Information, including BOXED Warning.


An easy-to-use online resource for 24/7 XYREM education and support. Signing up is an easy but important resource in your treatment journey.

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XYREM CareConnect®

If your healthcare provider prescribes XYREM to you, know that you will have lots of support along the way. XYREM CareConnect offers access to information, resources and programs that can help support you on XYREM.

XYREM CareConnect also gives you the chance to be in contact with a fellow XYREM patient, through the XYREM Patient Connection Mentor Program, to learn more about 2 common symptoms of narcolepsy–EDS and cataplexy–and treatment with XYREM. In addition, Jazz Pharmaceuticals is committed to making sure that those who may benefit from XYREM can affordably get it. Several different options are available for qualified patients.

Speak with a real XYREM patient

The XYREM Patient Connection Mentor Program lets you speak with a XYREM patient who understands your journey with narcolepsy.


Support to help you stay on track throughout your XYREM treatment

Taking XYREM may mean making lifestyle adjustments so that treatment becomes part of your routine. The Inspire program is here to help you stay on track with helpful information to fit your individual needs. When you enroll, you will receive regular messages of support and encouragement, useful treatment tips, and more.

You will get information on a variety of important topics, including:

  • What to expect from XYREM treatment
  • Understanding EDS and cataplexy in narcolepsy
  • Starting and staying on a routine for taking XYREM
  • Establishing healthy sleep habits
  • Boosting your support network—by communicating with friends, family, and healthcare providers

In addition, you can customize your level of support by choosing to receive this information by emails, text messages, or both.

Learn, plan, track, and more with the Inspire+ app

Inspire+ is a free, easy-to-use app that gives you useful tools and information to help you take control of your XYREM treatment on a day-to-day basis. Among other benefits, Inspire+ helps you plan your dosing schedule, set convenient reminders and alarms, quickly access information about taking XYREM, and track your progress over time.

Enroll now to get the benefits of customized support from Inspire.


Support all along the waY

Ongoing information about XYREM

Your healthcare provider is always your first source of information about the proper use of XYREM. In addition, Nurse Case Managers at the Certified Pharmacy are available as another resource for information about XYREM. Pharmacists from the Certified Pharmacy are also available to answer your questions about XYREM 24 hours a day, 7 days a week.

Helping make treatment more affordable

Jazz Pharmaceuticals is committed to making sure that those who may benefit from XYREM can affordably get it. Several different options are available for qualified patients based on personal needs. A Reimbursement Specialist can explain the details of all these programs to you and help determine if one is right for you.

Insurance and reimbursement support to help you understand how XYREM fits in your existing insurance coverage; works with a healthcare provider on accessing any necessary paperwork needed.

The XYREM Coupon Program offers a reduction in out-of-pocket expenses to eligible patients. The XYREM Coupon Program can cover monthly out-of-pocket expenses, including co-pays and any plan deductible. Eligible patients can pay no more than $35 dollars per prescription, subject to a maximum annual benefit.

The XYREM Coupon Program applies to patients who have provided consent to services offered by XYREM CareConnect. The XYREM Coupon Program is only available for residents of the US and Puerto Rico who have commercial insurance with co-pay/co-insurance exceeding $35 per prescription fill. Patients ineligible for the XYREM Coupon Program include but are not limited to those enrolled in Medicare Part D, Medicaid, Medigap, VA/DoD (Tricare) programs, the Indian Health Service, or any other federal or state-funded healthcare program, or where prohibited by law. The XYREM Coupon Program is not prescription drug coverage or insurance. Patients cannot seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through the XYREM Coupon Program.

Jazz Pharmaceuticals reserves the right to terminate or modify this program at any time with or without notice. Other terms and conditions apply.

No enrollment is required. Eligibility is assessed as part of the standard benefit investigation process performed by the pharmacy Reimbursement Specialist. Any Coupon benefit will be automatically deducted from the patient’s co-pay or other out-of-pocket cost with a patient’s verbal approval.

The XYREM Patient Assistance Program (PAP) is available for those with additional financial needs. If you meet certain financial criteria, such as having a low income level, are uninsured or underinsured, you may be eligible to receive XYREM at no cost.

XYREM Patient Connection Mentors—
there to share

We owe it to ourselves to help each other through this.

MichelleEDS & cataplexy in narcolepsy


The XYREM Patient Connection Mentor Program gives you the chance to be in contact with fellow XYREM patients. That way, you can learn more about living with 2 common symptoms of narcolepsy, EDS and cataplexy, and treatment with XYREM from someone else with firsthand experience. These individuals, called XYREM Mentors, are available to speak with you by phone.

Connect with a XYREM Mentor


or call 1-888-200-1128