¤
Narcolepsy is a neurological sleep disorder that can begin at any age and continues
throughout life. The onset typically occurs during the teens or early twenties but it can
also appear later in life. Predisposition to it seems to be hereditary. It is believed to affect
approximately 1 in every 2000 people of both sexes and all races. It is not degenerative;
therefore, people with narcolepsy can expect to live a normal life span.
¤
Major Daytime Symptoms include EDS and cataplexy.
¤
EDS, which includes daytime sleep attacks that may occur with or without warning and
which may be uncontrollable; persistent drowsiness, which may continue for prolonged
periods of time; and microsleeps, or fleeting moments of sleep, which may intrude into
the waking state.
¤
Cataplexy is a sudden loss of voluntary muscle control, usually triggered by emotions
such as laughter, surprise, fear, or anger. Cataplexy may occur more frequently during
times of stress or fatigue. The cataplectic attack may involve only a slight feeling of weakness
and limp muscles (ie., sagging facial muscles, a nodding head, buckling knees, loss of arm
strength, garbled speech), or it may result in immediate and total body collapse, during
which the person may appear unconscious, but is actually awake and alert. These attacks
may last from a few seconds up to several minutes. Cataplectic episodes are related to the
loss of muscle tone usually associated with the normal dreaming stage of sleep called rapid
eye movement (REM); as a protection against acting out one's dreams, the muscles become
immobile or paralyzed.
Directory
organized by subject, including
Medicine
.
Xyrem, FDA approved for EDS and Cataplexy in patients with Narcolepsy
Login Page
Search Results
Overview
What Is Xyrem?
Taking Xyrem
Safety
Finding a Physician
Do I need Xyrem?
Patient Success Program
Sleep Resources
Patient FAQ
Reference Section
Decrease Excessive Daytime Sleepiness
Increase In Daytime Wakefulness
Reduce Cataplexy
Clinical Global Impression of Change
Mechanism of Action
Dosing & Administration
Safety
Physician Success Program (Rx Forms)
References
Resource Center